Εξειδίκευση τύπου :	Άρθρο σε περιοδικό τύπο
Τίτλος:	Metabolic Effects of Dietary Chlorella vulgaris Evaluated by Multiorgan Metabolomics in Weaning Piglets
Δημιουργός/Συγγραφέας:	Pedro, Miguel F. [EL] Ματζαπετάκης, Μανόλης[EN] Matzapetakis, Manolis Maia, Margarida R. G. Fonseca, António J. M. Cabrita, Ana R. J. Alves, Susana P. Freire, João P. B. Bessa, Rui J. B. [EL] Ζερβού, Μαρία[EN] Zervou, Maria Almeida, André M.
Ημερομηνία:	2025
Γλώσσα:	Αγγλικά
ISSN:	2692-1952 2692-1952
DOI:	10.1021/acsagscitech.5c00646
Περίληψη:	Nutritional and bioactive potential of Chlorella vulgaris microalgae and/or probiotics have motivated research on the effects of dietary inclusion on piglet growth performance, though physiological effects are understudied. To examine these effects, we employed NMR-based untargeted profiling in the liver and intestines along with fatty acid composition of intramuscular fat in piglets fed a diet with 5% C. vulgaris, without (CV5) or with probiotics (CV5P), compared with a conventional diet (Control). Intestinal and hepatic metabolomes show differentiation of microalgae-fed groups from the Control. Colon contents revealed fermentation products as explanatory metabolites, alongside reduced amino acid fermentation, reducing inflammation. Liver metabolites point to glutathione pathway enhancement and altered carbohydrate and amino acid metabolism, benefiting piglet health. Increased levels of intramuscular omega-3 fatty acids were observed, which are important for pork quality. No effect on the ileum was observed. The probiotic had limited results but improved muscle accretion. Metabolomics revealed bioactivities imparted by C. vulgaris dietary inclusion, which are potentially important for development of algal applications in feed.
Τίτλος πηγής δημοσίευσης:	ACS Agricultural Science & Technology
Τόμος/Κεφάλαιο:	5
Τεύχος:	11
Θεματική Κατηγορία:	[EL] Χημική Βιολογία[EN] Chemical Biology [EL] Μικροβιολογία[EN] Microbiology [EL] Γεωργία (Γενικά)[EN] Agriculture (General) [EL] Βιοχημεία[EN] Biochemistry [EL] Φασματοσκοπία[EN] Spectroscopy [EL] Κτηνοτροφία[EN] Animal culture [EL] Φυσιολογία[EN] Physiology
Λέξεις-Κλειδιά:	Alternative feeds Chlorella vulgaris GC-MS metabolomics NMR metabolomics Piglets Probiotics
Κάτοχος πνευματικών δικαιωμάτων:	© 2025 American Chemical Society
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://doi.org/10.1021/acsagscitech.5c00646
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο