Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Cyclodextrins-block copolymer drug delivery systems: From design and development to preclinical studies
Δημιουργός/Συγγραφέας:	Saitani, Elmina-Marina Selianitis, Dimitrios Pippa, Natassa [EL] Πίσπας, Στέργιος[EN] Pispas, Stergios Valsami, Georgia
Ημερομηνία:	2024
Γλώσσα:	Αγγλικά
ISSN:	2191-9097
DOI:	10.1515/ntrev-2023-0204
Περίληψη:	Cyclodextrin (CD)-block copolymer hybrid systems have recently received great attention from the pharmaceutical and materials research community because this combination can result in new biomaterials and supramolecular structures, which possess the physicochemical and thermotropic properties of both classes of materials. Different structures of CD-block copolymer systems have been described (i.e., micelles, vehicles, core-shell structures, nanospheres, and membranes) and they can encapsulate active pharmaceutical ingredients or other bioactive compounds. The aim of this review is to summarize several examples, the properties, the morphological and physicochemical characteristics, the added value, the techniques used for their preparation and characterization, as well as the limitations of CD-block copolymer systems. Taking into consideration the wide variety of block copolymers and CD materials and the expected beneficial characteristics/behavior following their complexation, we could suggest them as new-generation formulations in the upcoming years.
Τίτλος πηγής δημοσίευσης:	Nanotechnology Reviews
Τόμος/Κεφάλαιο:	13
Τεύχος:	1
Θεματική Κατηγορία:	[EL] Φαρμακευτική[EN] Pharmacy and materia medica [EL] Νανοτεχνολογία[EN] Nanotechnology [EL] Φυσική και θεωρητική χημεία[EN] Physical and theoretical chemistry
Λέξεις-Κλειδιά:	biodegradable block copolymers drug delivery systems cyclodextrins hybrid nanosystems
Κάτοχος πνευματικών δικαιωμάτων:	© 2024 the author(s), published by De Gruyter.
Όροι και προϋποθέσεις δικαιωμάτων:	This work is licensed under the Creative Commons Attribution 4.0 International License
Ηλεκτρονική διεύθυνση στον εκδότη (link):	doi.org/10.1515/ntrev-2023-0204
Εμφανίζεται στις συλλογές:	Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο